I've always had an affinity for unlikely mashups. I think they just work. And I've always thought that the gameplay in a call of cthulu game bears a striking similarity to an episode of scooby doo. So the thought of a comical cthuluian horror game is very appealing to me. And lo and behold but someone has taken the words from my mouth.
http://www.mindspring.com/~ernestm/cthulhu/
Now, I'm not sure my first choice of rules for this game would be d100 coc (I'd be more partial to cartoon action hour), but I think what was put together here works nicely.
Any takers out there on running this strange mix of musical, comedy, and sanity-bending horror?